The gallbladder, a small organ located beneath the liver, plays a vital role in digestion by storing and releasing bile, which helps break down fats. While often overlooked, the gallbladder can develop problems like gallstones, inflammation (cholecystitis), or even infections that can significantly impact a person’s health. Understanding who is at risk of gallbladder disease is crucial for early prevention and timely treatment.
Which People are at a Higher Risk of Gallbladder Disease?
Here are the key groups more likely to develop gallbladder issues, as explained by Dr Amita Jain, a leading laparoscopic surgeon and one of the best surgeons for gallbladder treatments in India.
1. Women – Women, especially those aged 20 to 60, are more prone to gallstones due to hormonal factors like estrogen. Pregnancy, birth control pills, and hormone replacement therapy can increase bile cholesterol, leading to gallstones.
2. People Over Age 40 – The risk of gallbladder disease increases with age, particularly after 40, due to slower bile movement and changes in metabolism.
3. Individuals with a Family History – Genetics play a role. If gallbladder disease runs in the family, your risk is higher.
4. People Who Are Overweight or Obese – Obesity increases cholesterol in bile, a major factor in gallstone formation. Rapid weight gain also stresses the gallbladder.
5. Those on Rapid Weight-Loss Diets or Fasting – Crash diets or long fasting periods can cause the liver to release extra cholesterol into the bile, increasing gallstone risk.
6. People with Diabetes – High insulin levels can lead to higher cholesterol levels in bile, increasing the chance of gallstone formation.
7. Individuals with Certain Medical Conditions – Liver disease, hemolytic anaemia, and Crohn’s disease can all elevate the risk of gallbladder problems.
8. People with a Sedentary Lifestyle – Lack of physical activity may contribute to obesity and slower digestion, both of which are linked to gallbladder disease.

Dr Amita Jain is one of India’s most distinguished and experienced female surgeons and proctologists, known for her unmatched expertise in general, advanced laparoscopic, and laser proctology surgery. With over 30 years of surgical excellence, Dr Amita Jain has built a reputation for precision, compassionate care, and advanced surgical techniques.
Dr Jain has successfully performed a wide range of complex general surgeries, including both open and minimally invasive procedures, with a strong focus on trauma care, onco-surgical techniques, and reconstructive surgeries. Her medical specialisation includes: gallbladder surgeries, appendix removal surgeries, hernia repair surgeries, Pilonidal Sinus treatments, varicose vein and piles surgeries, fistula surgeries and fissure surgeries.
Dr Jain, currently serves as Senior Consultant and Head of Department (General, Laser, Proctology and Laparoscopic Surgeries) across premier medical networks in South Delhi:
Daffodils by Artemis Hospitals: Spring Meadows, East of Kailash, New Delhi. Book Appointment
Fortis C-DOC Hospital: B-16, Chirag Enclave, New Delhi. Book Appointment
Rosewalk Luxury Multi-Specialty & Maternity Hospital: Panchsheel Park, New Delhi. Book Appointment
Rainbow Children’s Hospital: Malviya Nagar, New Delhi. Book Appointment
Learn More about Dr Amita Jain.
Dr Amita Jain has also authored some of the key medical journals and publications, like ResearchGate, IJSR
Note: This article is written and reviewed by Dr Amita Jain, while referring to her medical journals and publications.

